Henry Harmon Spalding (1803–1874), and his wife Eliza Hart Spalding (1807–1851) were prominent Presbyterian missionaries and educators working primarily with the Nez Perce in the U.S. Pacific Northwest. The Spaldings and their fellow missionaries were among the earliest Americans to travel across the western plains, through the Rocky Mountains and into the lands of the Pacific Northwest to their religious missions in what would become the states of Idaho and Washington. Their missionary party of five, including Marcus Whitman and his wife Narcissa and William H. Gray, joined with a group of fur traders to create the first wagon train along the Oregon Trail.