In Case of Emergency is an American half-hour comedy television series shown on ABC in the United States. The series follows a group of high school acquaintances whose lives have not turned out as they hoped. It premiered on January 3, 2007 at 9:30pm and ended on April 11, 2007. The pilot episode was directed by Jon Favreau and the cast included Jonathan Silverman, David Arquette, Lori Loughlin, Kelly Hu, and Greg Germann.