In the U.S. state of Virginia, Interstate 64 runs east–west through the middle of the state from West Virginia to the Hampton Roads region, a total of . It is notable for crossing the mouth of the harbor of Hampton Roads on the Hampton Roads Bridge-Tunnel, the first bridge-tunnel to incorporate artificial islands. Also noteworthy is a section through Rockfish Gap, a wind gap in the Blue Ridge Mountains, which was equipped with an innovative system of airport-style runway lighting embedded into the pavement to aid motorists during periods of poor visibility due to fog or other conditions.