The is a river that has both its source and its mouth in the city of Ise, Mie Prefecture, Japan. The river is notable because it flows through Ise Grand Shrine and, due to its strong association with the Shrine, many songs and poems have been written about it throughout history. The Uji Bridge in Uji, Kyoto, which serves as the entrance to Ise Grand Shrine, crosses the Isuzu River.