M-76 is a former state trunkline highway designation in the Lower Peninsula of the US state of Michigan. The highway's designation was decommissioned when the last section of it was converted to freeway as a part of the present-day Interstate 75 (I-75). At that time, M-76 extended from US Highway 23 (US 23) near Standish northwesterly to I-75 south of Grayling. Two sections of the route followed freeways with a two-lane highway in between to connect them. The former routing of M-76 through West Branch before that city was bypassed was initially redesignated Business M-76 (Bus. M-76). The highway itself ran through mixed fields and forests bypassing several other towns in the region.