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Macsyma
Macsyma (Project MAC’s SYmbolic MAnipulator) is one the oldest general purpose computer algebra systems, which is still widely used. It was originally developed from 1968 to 1982 at MIT as part of Project MAC. In 1982, Macsyma was licensed to Symbolics, and became a commercial product. Simultaneously, it remained available, from DOE, for academics and US government agencies. DOE version has been maintained by Bill Schelter, and, under the name of Maxima, became released under GPL license from 1999 on.

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