Medvedevsky District (; ) is an administrative and municipal district (raion), one of the fourteen in the Mari El Republic, Russia. It is located in the central and northern parts of the republic. The area of the district is . Its administrative center is the urban locality (an urban-type settlement) of Medvedevo. As of the 2010 Census, the total population of the district was 67,703, with the population of Medvedevo accounting for 24.9% of that number.