Mistissini ( meaning Big Rock) is a Cree town located in the south-east corner of the largest natural lake in Quebec, Lake Mistassini (120 km long by 30 km wide). The town is inside the boundaries of the Baie-James Municipality, and is the largest Cree community with a population of 3,427 people in 2011. The surface area of the town is 1380 km² (Category I land, as defined in the James Bay and Northern Quebec Agreement).