Mönckeberg's arteriosclerosis, or Mönckeberg's sclerosis, also called
medial calcific sclerosis, is a form of arteriosclerosis or vessel hardening, where calcium deposits are found in the muscular middle layer of the walls of
arteries (the
tunica media). It is an example of
dystrophic calcification.This condition occurs as an age related degenerative process.However it can happen in pseudoxanthomas elasticum and idiopathic arterial calcification of infancy like pathological condition also. Its clinical significance and etiology are not well understood and its relationship to
atherosclerosis and other forms of vascular
calcification are the subject of disagreement. Mönckeberg's arteriosclerosis is named after Johann Georg Mönckeberg, who first described it in 1903.