Pustoshkinsky District is an administrative and municipal district (raion), one of the twenty-four in Pskov Oblast, Russia. It is located in the south of the oblast and borders with Bezhanitsky District in the north, Novosokolnichesky District in the east, Nevelsky District in the south, Sebezhsky District in the west, and with Opochetsky District in the northwest. The area of the district is . Its administrative center is the town of Pustoshka. Population: 12,071 (2002 Census); The population of Pustoshka accounts for 49.2% of the district's total population.