São Cristóvão (, Saint Christopher) is a Brazilianmunicipality in the Northeastern state of Sergipe. Founded at the mouth of the Vaza-Barris River on January 1, 1590, the municipality is the fourth oldest settlement in Brazil. São Cristóvão is noted for its historic city square, São Francisco Square, and numerous early colonial-period buildings. The site was designated a UNESCOWorld Heritage Site in 2010.