Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. It is also known as RANTES (regulated on activation, normal T cell expressed and secreted).

SISD can refer to:

• Single Instruction, Single Data, a computer processor architecture
• CCL5, an 8kDa protein also using the symbol SISD
• Sixteen-segment display
• Several school districts in Texas. See List of school districts in Texas - S
• Saginaw Intermediate School District