Southwestern Indiana is an 11-county region of southern Indiana, United States located at the southernmost and westernmost part of the state. As of the 2010 census, the region's combined population is 474,251. Evansville, Indiana's third largest city, is the primary hub for the region as well as the primary regional hub for a tri-state area which includes Kentucky and Illinois. Other regional hubs include Jasper, Vincennes, and Washington.