US Highway 27 (US 27) is a part of the US Highway System that now runs from Miami, Florida, to Fort Wayne, Indiana. In the US state of Michigan, it was a state trunkline highway that entered the state south of Kinderhook and ended south of Grayling. Its route consisted of a freeway concurrency with Interstate 69 (I-69) from the state line north to the Lansing area before it followed its own freeway facility northward to St. Johns. From there north to Ithaca, US 27 was an expressway before continuing as a freeway to a terminus south of Grayling.