Signal transducing adaptor proteins are
proteins that are accessory to main proteins in a
signal transduction pathway. Adaptor proteins contain a variety of protein-binding modules that link protein-binding partners together and facilitate the creation of larger signaling complexes. These proteins tend to lack any intrinsic enzymatic activity themselves but instead mediate specific
protein–protein interactions that drive the formation of
protein complexes. Examples of adaptor proteins include
MyD88,
Grb2 and
SHC1.