Dyslipidemia is an abnormal amount of lipids (e.g., cholesterol and/or fat) in the blood. In developed countries, most dyslipidemias are
hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to
diet and lifestyle. Prolonged elevation of
insulin levels can also lead to dyslipidemia. Likewise, increased levels of
O-GlcNAc transferase (OGT) may cause dyslipidemia.