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Endothelin 3
Endothelin-3
is a
protein
that in humans is encoded by the
EDN3
gene
.
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Endothelin
Endothelins
are peptides that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (
hypertension
) and heart disease.
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