Sirene or Sirenje (, ; , ; Serbian/Croatian: сир, sir, Albanian: djath i bardhe) or known as "white brine sirene" (, ) is a type of brined cheese made in South-Eastern Europe, especially popular in Croatia, Serbia, Bulgaria, Romania, Albania,  Montenegro, the Republic of Macedonia, Greece and also in Israel. It is made of goat's milk, sheep milk, cow milk or a combination of milks. It is slightly crumbly with min. dry matter of about 46-48 nd fat content in dry matter of about 44-48%. It is commonly produced in blocks, and has a slightly grainy texture. It is used as a table cheese, as well as in salads and in baking.

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Sirene is a type of Bulgarian cheese. The word may also refer to:

• French frigate Sirène (1795), a French Navy sailing ship
• Sirène-class submarine, a pre-World War II class of French submarine
  • French submarine Sirène, scuttled in 1942, raised and sunk in 1944
• , a Royal Navy submarine loaned to France as Sirene from 1952 to 1958
• Sirene (barque), a barque wrecked in 1892