For the English football league, see Aetolian League (football).

The Aetolian League (also transliterated as Aitolian League) was a confederation of tribal communities and cities in ancient Greece centered on Aetolia in central Greece. It was established, probably during the early Hellenistic era, in opposition to Macedon and the Achaean League. Two annual meetings were held in Thermika and Panaetolika. It occupied Delphi from 290 BC and gained territory steadily until, by the end of the 3rd century BC, it controlled the whole of central Greece outside Attica and Boeotia. At its peak, the league's territory included Locris, Malis, Dolopes, part of Thessaly, Phocis, and Acarnania. In the latter part of its power, certain Greek city-states joined the Aetolian League such as the Ardadian cities of Mantineia, Tegea, Figaleia and Kydonia on Crete.