Brockmann body is an
endocrine organ in some
teleost fish, and is composed of a collection of islet tissues. The islet tissues are in turn composed of endocrine cells which are the principal sites of
insulin synthesis. They are distributed around the spleen and the large intestine. They also secrete other hormones such as
glucagon and
somatostatin. Hence, Brochmann body is the centre of control of
blood glucose level in these fishes. Glucagon is also produced from the intestine, but Brockmann body is the major source. Increased level of glucose stimulate the Brockmann body to release insulin, while inhibiting glucagon. Somatostatin released from Brockmann body inhibits cells to produce insulin and glucagon. In addition it inhibits release of
growth hormone from the
pituitary. It is named after a German physician Heinrich Brochmann who discovered it in 1848.