The Inland Empire (I.E.) is a region in Southern California. The term may be used to refer to the cities of western Riverside County and southwestern San Bernardino County. A generally broader definition will include eastern Los Angeles County cities in the Pomona Valley, and/or the desert community of Palm Springs as well as its surrounding area; a much larger definition will include all of San Bernardino and Riverside counties.

Inland Empire is a 2006 film written and directed by David Lynch and was his first feature film since 2001's Mulholland Drive. The feature took two-and-a-half years to complete, and was Lynch's first film to have been shot entirely in standard definition digital video. The film is a co-production of France, Poland and the United States. It premiered in Italy at the Venice Film Festival on 6 September 2006.