Mother's Little Helper

"Mother's Little Helper" is a song by the English rock and roll band The Rolling Stones. It first appeared as the opening track to the United Kingdom version of their 1966 album Aftermath.

Mother's Little Helpers or Mother's Little Helper may refer to:

• Nickname for the drug Diazepam (Valium)
• Cougars, Inc., developed under the title Mother's Little Helpers, a 2010 indie film
• "Mother's Little Helper", a 1966 Rolling Stones song
• "Mother's Little Helper" (Medium), a Medium episode
• "Mother's Little Helper", a Casualty (series 11) episode