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Additional
NYX (gene)
English Wikipedia - The Free Encyclopedia
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Nyctalopin
Nyctalopin
is a
protein
that in humans is encoded by the
NYX
gene
. It is a
leucine
-rich
proteoglycan
which is
expressed
in the eye, spleen and brain in mice. Mutations in this gene cause
congenital stationary night blindness
in humans. A
mouse strain
called nob (no
b-wave
) carries a spontaneous mutation leading to a
frameshift
in this gene. These mice are used as an
animal model
for congenital stationary night blindness.
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