State Route 65 (
SR 65) is a north–south highway in western
Ohio. Its southern terminus is at
State Route 47 near
Sidney, and its northern terminus is at its interchange with
Interstate 280 in
Toledo. From south to north, the route passes through the cities of
Jackson Center,
Uniopolis,
Lima,
Columbus Grove,
Ottawa,
Leipsic,
Belmore,
McClure,
Grand Rapids,
Perrysburg,
Rossford, and
Toledo.