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Additional
graded potential
English Wikipedia - The Free Encyclopedia
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Graded potential
Graded potentials
are changes in
membrane potential
that vary in size, as opposed to being
all-or-none
. They arise from the summation of the individual actions of
ligand-gated ion channel
proteins, and decrease over time and space. They do not typically involve
voltage-gated
sodium
and
potassium channels
. These impulses are incremental and may be excitatory or inhibitory. They occur at the
postsynaptic
dendrite
as a result of presynaptic
neuron
firing
and release of
neurotransmitter
, or may occur in
skeletal
,
smooth
, or
cardiac muscle
in response to
nerve
input. The magnitude of a graded potential is determined by the strength of the stimulus.
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