Hair cells are the
sensory receptors of both the
auditory system and the
vestibular system in all
vertebrates. Through
mechanotransduction, hair cells detect movement in their environment. In
mammals, the auditory hair cells are located within the
organ of Corti on a thin
basilar membrane in the
cochlea of the inner
ear. They derive their name from the tufts of
stereocilia that protrude from the apical surface of the cell, a structure known as the hair bundle, into the
scala media, a fluid-filled tube within the cochlea.
Mammalian cochlear hair cells come in two anatomically and functionally distinct types: the
outer and
inner hair cells. Damage to these hair cells results in decreased hearing sensitivity, i.e.
sensorineural hearing loss, and because human hair cells are incapable of regeneration, this damage is permanent. However, other organisms, such as the frequently studied
zebrafish, have regenerating hair cells.