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Additional
AP endonuclease
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AP endonuclease
Apurinic/apyrimidinic (AP)
endonuclease
(
BRENDA
= 4.2.99.18) is an
enzyme
that is involved in the
DNA
base excision repair
pathway (BER). Its main role in the repair of damaged or mismatched
nucleotides
in DNA is to create a nick in the
phosphodiester
backbone of the
AP site
created when
DNA glycosylase
removes the damaged base.
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