Clayton-le-Moors is a village in Hyndburn in Lancashire, England. The village is locally referred to as 'Clayton'. There is also a ward with the same name in Hyndburn. The population of this ward at the 2011 census was 4,725. To the west lies Rishton, to the north Great Harwood, and two miles to the south, Accrington. Clayton-le-Moors is situated on the A680 road alongside the M65 motorway.