Dorogobuzhsky District is an administrative and municipal district (raion), one of the twenty-five in Smolensk Oblast, Russia. It is located in the center of the oblast. The area of the district is . Its administrative center is the town of Dorogobuzh. Population: 29,077 (2010 Census); The population of Dorogobuzh accounts for 36.9% of the district's total population.