An
immobilized enzyme is an
enzyme that is attached to an inert, insoluble material such as calcium alginate (produced by reacting a mixture of
sodium alginate solution and enzyme solution with calcium chloride). This can provide increased resistance to changes in conditions such as
pH or
temperature. It also allows enzymes to be held in place throughout the reaction, following which they are easily separated from the products and may be used again - a far more efficient process and so is widely used in industry for
enzyme catalysed reactions. An alternative to enzyme immobilization is
whole cell immobilization.