Factor XIII

Factor XIII or fibrin stabilizing factor is an enzyme  of the blood coagulation system that crosslinks fibrin. Deficiency of this factor (FXIIID) affects clot stability. FXIIID, while generally rare, Iran with 473 cases has the highest global incidence of disorder; the city of Khash has the highest incidence in Iran as it is in sistan and Baluchestan province with high rate of consanguineous marriage.