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Additional
Immunoglobulin E
English Wikipedia - The Free Encyclopedia
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Immunoglobulin E
Immunoglobulin E
(
IgE
) is a kind of
antibody
(or
immunoglobulin
(Ig) "
isotype
") that has only been found in
mammals
. Monomers of IgE consist of two heavy chains (e chain) and two light chains, with the e chain containing 4 Ig-like constant domains (Ce1-Ce4). IgE's main function is
immunity
to parasites such as
helminths
like
Schistosoma mansoni
,
Trichinella spiralis
, and
Fasciola hepatica
. IgE is utilized during immune defense against certain
protozoan
parasites
such as
Plasmodium falciparum
.
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