Interstate 40 (
I-40) is a major
Interstate Highway running through the south-central portion of the United States generally north of
Interstate 10 and
Interstate 20 but south of
Interstate 70. The western end is at
Interstate 15 in
Barstow, California; its eastern end is at a
concurrency of
U.S. Route 117 and
North Carolina Highway 132 in
Wilmington, North Carolina. Much of the western part of I-40, from
Oklahoma City to
Barstow, parallels or overlays the historic
U.S. Route 66, east of Oklahoma City the route generally parallels
U.S. Route 64 and
U.S. Route 70. I-40 runs through many major cities including
Raleigh, North Carolina;
Nashville, Tennessee;
Memphis, Tennessee;
Little Rock, Arkansas;
Oklahoma City, Oklahoma;
Amarillo, Texas, and
Albuquerque, New Mexico.