Lois Patrice Griffin (also
Pewterschmidt) is one of the main characters of the
animated television series
Family Guy. She is voiced by writer
Alex Borstein and first appeared on television, along with the rest of the family, in the 15-minute short on December 20, 1998. Lois was created and designed by series creator
Seth MacFarlane. MacFarlane was asked to pitch a pilot to the
Fox Broadcasting Company based on
Larry and Steve, a short he made which featured a middle-aged character named Larry and an intellectual dog, Steve. After the pilot was given the green light, the Griffin family appeared on the episode "
Death Has a Shadow".