Mescalero or Mescalero Apache is an Apache tribe of Southern AthabaskanNative Americans. The tribe is federally recognized as the Mescalero Apache Tribe of the Mescalero Apache Reservation in southcentral New Mexico. In the nineteenth century, the Mescalero opened their reservation to other Apache bands, such as the Mimbreno and the Chiricahua who had been imprisoned in Florida, and the Lipan Apache.