RNA extraction is the purification of
RNA from biological samples. This procedure is complicated by the ubiquitous presence of
ribonuclease enzymes in cells and tissues, which can rapidly degrade RNA. Several methods are used in
molecular biology to isolate RNA from samples, the most common of these is
Guanidinium thiocyanate-phenol-chloroform extraction. The filter paper based lysis and elution method features high throughput capacity.