Saint Zoe of Rome (d. ca. 286) was a
noblewoman, married to Nicostratus, a high
Roman court official. For six years she had been unable to speak. St Sebastian made the Sign of the Cross over the woman, and she immediately began to speak and she glorified the Lord. Nicostratus and his wife asked for Baptism. She lived during Emperor
Diocletian's early persecution of the
Christian Church.