U.S. Route 41 (
US 41) in the U.S. state of
Illinois runs north from the Indiana border beneath the
Chicago Skyway on Indianapolis Boulevard to the Wisconsin border north of the northern terminus of the
Tri-State Tollway with
Interstate 94. It is the only north–south U.S. Route to travel through a significant portion of the city of
Chicago, carrying
Lake Shore Drive through the central portion of the city along the lakefront. US 41 in Illinois is in length.