Translate:
English
Chinese (S)
Chinese (T)
Croatian
Dutch
French
German
Hebrew
Italian
Japanese
Korean
Portuguese
Russian
Serbian
Spanish
Swedish
Turkish
Additional
buprenorphine/naloxone
English Wikipedia - The Free Encyclopedia
Download this dictionary
Buprenorphine/naloxone
Buprenorphine/naloxone
(brand name
Suboxone
) is a
combination drug
formulation
of
buprenorphine
, a
μ-opioid receptor
(MOR) weak
partial agonist
and
κ-opioid receptor
antagonist
, and
naloxone
, a MOR
silent antagonist
, in a 4:1 ratio. It is used in the treatment of
opioid dependence
. The purpose of naloxone is to deter
intravenous
abuse
;
parenteral
administration rapidly induces
opioid withdrawal
symptoms, while regular, intended use does not (as naloxone is minimally
bioavailable
with sublingual ingestion). In spite of the fact that the drug is intended to treat opioid dependence, it is still
addictive
.
See more at Wikipedia.org...
© This article uses material from
Wikipedia
®
and is licensed under the
GNU Free Documentation License
and under the
Creative Commons Attribution-ShareAlike License