Bupropion or
bupropion hydrochloride, also known formerly as
amfebutamone, is a
medication primarily used as an
antidepressant and
smoking cessation aid. It is marketed as
Wellbutrin and
Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States, although in many English-speaking countries, including the United Kingdom, Australia and New Zealand, this is an
off-label use. Bupropion is taken in tablet form and is available only by prescription in most countries. Chemically, bupropion is in the
aminoketone family.