Cell–cell interaction refers to the direct interactions between
cell surfaces that play a crucial role in the
development and function of
multicellular organisms. These interactions allow cells to
communicate with each other in response to changes in their microenvironment. This ability to send and receive signals is essential for the survival of the cell. Interactions between cells can be stable such as those made through
cell junctions. These junctions are involved in the communication and organization of cells within a particular tissue. Others are transient or temporary such as those between cells of the
immune system or the interactions involved in tissue
inflammation. These types of intercellular interactions are distinguished from other types such as those between cells and the
extracellular matrix. The loss of communication between cells can result in uncontrollable cell growth and cancer.