Gastric outlet obstruction (often abbreviated as
GOO) is a medical condition where there is an obstruction at the level of the
pylorus, which is the outlet of the
stomach. Individuals with gastric outlet obstruction will often have recurrent vomiting of food that has accumulated in the stomach, but which cannot pass into the
small intestine due to the obstruction. The stomach often dilates to accommodate food intake and secretions. Causes of gastric outlet obstruction include both benign causes (such as
peptic ulcer disease affecting the area around the pylorus), as well as malignant causes, such as
gastric cancer.