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Additional
glucuronidation
English Wikipedia - The Free Encyclopedia
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Glucuronidation
Glucuronidation
, more correctly
glucuronosylation
, is the addition of
glucuronic acid
to a substrate. Glucuronidation is often involved in
xenobiotic metabolism
of substances such as
drugs
, pollutants,
bilirubin
,
androgens
,
estrogens
,
mineralocorticoids
,
glucocorticoids
,
fatty acid
derivatives,
retinoids
, and
bile acids
. These linkages involve
glycosidic bonds
.
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