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Additional
myoepithelial cell
English Wikipedia - The Free Encyclopedia
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Myoepithelial cell
Myoepithelial cells
(sometimes referred to as
myoepithelium
) are cells usually found in
glandular epithelium
as a thin layer above the
basement membrane
but generally beneath the
luminal
cells. These may be positive for
alpha smooth muscle
actin
and can contract and expel the
secretions
of
exocrine glands
. They are found in the
sweat glands
,
mammary glands
,
lacrimal glands
, and
salivary glands
. Myoepithelial cells in these cases constitute the
basal cell layer
of an
epithelium
that harbors the epithelial
progenitor
. In the case of wound healing, myoepithelial cells reactively
proliferate
. Presence of myoepithelial cells in a
hyperplastic
tissue proves the benignity of the gland and, when absent, indicates
cancer
. Only rare cancers like
adenoid cystic carcinomas
contains
myoepithelial cells
as one of the
malignant
components.
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