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Additional
reuptake inhibitor
English Wikipedia - The Free Encyclopedia
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Reuptake inhibitor
A
reuptake inhibitor
(
RI
) is a type of
reuptake modulator
which inhibits the
plasmalemmal
transporter
-mediated
reuptake
of a
neurotransmitter
from the
synapse
into the
pre-synaptic neuron
, leading to an increase in the
extracellular
concentrations
of the
neurotransmitter
and therefore an increase in
neurotransmission
. Various
drugs
to exert their
psychological
and
physiological
effects through reuptake inhibition, including many
antidepressants
and
psychostimulants
.
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