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Additional
steroid hormone receptor
English Wikipedia - The Free Encyclopedia
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Steroid hormone receptor
Steroid hormone receptors
are found in the
nucleus
,
cytosol
, and also on the
plasma membrane
of target cells. They are generally
intracellular receptors
(typically cytoplasmic or nuclear) and initiate
signal transduction
for
steroid hormones
which lead to changes in gene expression over a time period of hours to days. The best studied steroid hormone
receptors
are members of the
nuclear receptor
subfamily 3 (NR3) that include receptors for
estrogen
(group NR3A) and 3-ketosteroids (group NR3C). In addition to nuclear receptors, several
G protein-coupled receptors
and
ion channels
act as
cell surface receptors
for certain steroid hormones.
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