systemic

Systemic refers to something that is spread throughout, system-wide, affecting a group or system, such as a body, economy, market or society as a whole. Systemic may also refer to:

In medicine, systemic means affecting the whole body, or at least multiple organ systems. It is in contrast with topical or local.

• Systemic administration, a route of administration of medication so that the entire body is affected
• Systemic circulation, carries oxygenated blood from the heart to the body and then returns deoxygenated blood back to the heart
• Systemic disease, an illness that affects multiple organs, systems or tissues, or the entire body
• Systemic effect, an adverse effect of a medical treatment that affects the body as a whole, rather than one part
• Systemic inflammatory response syndrome, an inflammatory state affecting the whole body, frequently in response to infection
• Systemic lupus erythematosus, a chronic autoimmune connective tissue disease that can affect any part of the body
• Systemic scleroderma, also known as systemic sclerosis, a systemic connective tissue disease
• Systemic venous system, refers to veins that drain into the right atrium without passing through two vascular beds
• Systemic exertion intolerance disease, a new name for chronic fatigue syndrome proposed by the Institute of Medicine in 2015